Professional Detailing1 min read

Bulk Coating Laboratory Calculations: Multiply Serial Dilution Factors

When a laboratory method specifies successive dilutions, the combined concentration factor is multiplicative. Keep the preparation record clear enough to distinguish a fraction of the previous solution from a fraction of the original.

Updated · NANOLAB Knowledge

The key distinction

A one-in-ten concentration followed by a one-in-five concentration of that prepared solution gives one-fiftieth of the original concentration. Adding ten and five would describe a different and incorrect calculation.

Practical checks

  1. Confirm how the approved method defines each dilution.
  2. Record the concentration basis and units.
  3. Calculate the cumulative factor and have the preparation record checked.

Example

Arithmetic example: an original concentration represented by one hundred units becomes ten units after a tenfold dilution and two units after a subsequent fivefold dilution, on the same stated concentration basis.

Scope and limits

This is an illustrative calculation for approved laboratory work. It is not an instruction to dilute NANOLAB coatings, add a solvent or change application chemistry; follow the product-specific and laboratory instructions.

Related guidance

Ask NANOLAB about the exact product and intended use. Use the current product documentation for formulation-specific instructions.